Vision


 To be a distinguished center in parasitological research, providing high quality research at both diagnostic and treatment levels

  Mission


 To provide a high quality of diagnostic laboratory service in an effective and timely manner in addition to develop new diagnostic techniques for endemic parasitic diseases 

  Head of the Laboratory


  Former Heads And Staff Members


Former Heads


Emeritus Prof. Hessien El Nahal 

Emeritus Prof. Soad Ismail     

Emeritus Prof. Nemait Amr 

Emeritus Prof. Hoda Yakoub Sabry 

Emeritus Prof. Maisa Ahmed Shalaby 

 

Staff Members


Emeritus Prof.  Amal Mohamed Abdou

Emeritus Prof. Fatem Ramzy Guirguis

Emeritus Prof. Soheir Sayed Mohammed Mahmoud

Emeritus Prof. Zeinab Hassanien Fahmy

Emeritus Prof. Mohamed Abdel Gayid

Emeritus Prof. Eman Aly Muostafa

Emeritus Assistant.Prof. Wafaa Mohamed Abdel Fatah

Emeritus Assistant.Prof. Eman Ahmed Hassan

Prof. Nevine Guirguis Nessim

Prof. Samia William Abdel Sayed

Prof. Tarek Mahmoud Diab

Prof. Rabab El-Sayed Mohamed

Ass.Prof. Gehan Labib Hafez

Ass.Prof. Azza Moustafa Fahmy

Lecturer: Shimaa Shaker

Lecturer: Hagar Fathy

Lecturer: Eman EL-Shabrawy

Ass. Lecturer: Shimaa Fouad

Ass. Lecturer: Mena El Rahman Ahmed Fahmy

Specialist: Al-Zahraa Mosallam Awadallah

Specialist: Reem Ahmed El Sheik

Specialist: May Abdel Wehab Mohamed

Specialist: Shaimaa Fathy Foud

Specialist: Pola Robil Michael

Specialist: Noran Abd El Nasser Al Brolos

Specialist: Maha Taalat El Hanafy Mahmoud

  Field of Research



a.Implementation and update of diagnostic techniques in managing endemic parasitic infections and their complications.

b- Evaluation and monitoring of drug efficacies and emergence of resistance

c- Development of new candidate vaccines against parasites.

d- Implications of molecular techniques in medical parasitological studies.

e- Utilization of nanotechonology in various research fields.

  Main Achievements


 a. Three innovative prototypes were submitted to the Egypian Patency Office, Academy of Scientfic Research and Technology:

The establishment of a nano-chip as a rapid and multiple detector to diagnose parasites. Patency is pending (submitted in 2017, no. 837). PI: Prof. Ibrahim R. Aly

 •      Web-based Diagnosis of parasitic diseases using I-Phone. Temporary patency is issued(submitted in 2016, no. 16). PI: Associate Prof. Gehan Labib Hafez, Associate Prof. Rabab Sayed Zalat and Prof. Dr. Ibrahim Aly

 •    Preparation of Single-domain antibodies and graphene coated magnetic metal nanoparticles. Patency is pending (submitted in 2015, no. 14/235). PI: Prof. Ibrahim R. Aly

b.       Identification, characterization and preparation of target antigens of different parasites of medical importance and using them in both diagnosis and treatment of these parasites.

c.      Evaluation of newly introduced  drugs and purified plant extracts as antiparasitic agents

d.       Application of newly introduced molecular techniques in the diagnosis of endemic parasites

 

  Running Techniques


  • Services

A. Routine urine and stool microscopic examinations using different parasitological techniques.

B. Introduction of special new techniques for stool analysis as parasep faecal concentration technique including

  • Diagnosis and identification of different opportunistic protozoa in stool samples using different staining techniques including Zeihl Neelsen, Modified acid fast, Trichrome and modified trichrome as well as Safranine stains.

  • Performing special staining methods or culture media for detection of newly emerging protozoa (D. fragilis & B. hominis) as Giemsa stain

  • Applying special stains for detection of protozoa as Safranine Stain & Auramine Rhodamine  Stains.

D. Field surveys using specific parasitological techniques including nucleopore filtration of urine for S. haematobium ova, Kato technique for different parasitic ova in stool and Negrosine technique for different parasitic ova in stool.

E. Diagnosis of different parasites and protozoa in stool samples using immunoparasitological assays (our lab prepared assays or newly introduced kits) including:-

  • ELISA kits for detection of circulating parasitic antigens in patients' sera as well as copro-antigens in patients' stool Merifluor immunofluorescent stain.

  • Applying a modified method for the direct wet mount preparation for better and clear identification of parasites.

F. Periodic parasitological examination of personnel and workers in different labs, especially those subjected to contamination with biological materials.

 

  • Research               

A. Standard experimental parasitological examinations to measure the intensity of schistosomal infection and morbidity including:

  • Worm perfusion to count the number of worms present in liver and intestine of infected mice.

  • Ova count in tissues (liver and intestine)

  • Oogram pattern (counting different developmental stages of the parasites' ova in small intestine.

B. Identification, characterization and preparation of target antigens of different parasites of  medical  importance  in large amounts  using  molecular  biological tools and applying it in:-

  • Development of simple, sensitive, less time consuming and cheap kits using nanotechnology for diagnosis of different multiple parasites (as ELISA plate, coated by different antigens) (screening test).

  • Production of highly sensitive and specific antibodies against these target antigens using phage display technique and applying it in diagnostic kits.

  • Development of candidate vaccines.

  • Production of nanoparticles as a drug delivery system for targeting of parasitic infections.

  • Development of a quick diagnostic strip kit for field surveys (running) from rabbits, on strip or ring, for the detection of Copro-antigens of different parasites (Schistosoma and Fasciola to start with..) could be applied commercially.

C. Tissue culture unit which is used in:-

  • In vitro culture of parasites for immunolocalization studies

  • Maintenance of life cycle of some parasites and protozoa (Schistosoma, Toxoplasma, Cryptospordium and Blastocystis) and production of target antigens and biological materials secreted from these parasites.

  • Evaluation of antiparasitic efficacy of newly introduced drugs and plant extracts as well as classical drug treatment either alone or combined with other materials including anti-inflammatory, antifibrotic agents, natural and newly introduced synthetic compounds.

  • Evaluation of different vaccines against parasites

 

  Laboratory Structure and Facilities


The department consists of two research laboratories and one outpatient clinic laboratory equipped with basic facilities for parasitological tests including laminar flow, water purification system, water bath, perfusion system, balances, centrifuge, PCR device, FTIR-Spectroscopy, SDS-Electrophoresis, Immunoblot, binocular light microscope, digital microscope, florescent microscope, stereo microscope, CO2 incubator and Electroborator.

  Training facilities


a. Annual training program for laboratory personnels working on the diagnosis of parasitic diseases.

b. Two weeks rotation program in the outpatient parasitology lab for Faculty of Medicine and Science undergraduate students.

c.  Annual teaching of parasitology course for TBRI nursing school students.

  Scope of Services


The policy of the department is to analyze urine and stool samples of immuncompetent and immunocomprornised patients using different parasitological techniques for both inpatients and outpatients. Also, to perform monthly statistical analysis for data.

The scope of services offered by the department focus on:

a. Gastrointestinal diseases, urinary tract infections, Some blood stream parasites (e.g. toxoplasma), Fever of unknown origin, Post-surgical parasitic infections as well as infections related to compromised immunity in hepatic and chronic renal patients.

b.  Monitoring of drug efficacy and emergence of drug resistance parasitic isolates (strains) including Schistosomiasis mansoni and hematobium, Fascioliasis (hepatica and gigantica) and Protozoa e.g., Entamebia species (histolytica and dispar).

  Projects


 Internal research projects:


Nanoparticles as a drug delivery system for targeting of schistosomiasis and fascioliasis. PI: Prof. Ibrahim Aly (2011)

The pathophysiological variability of different Blastocystis hominis isolates in experimental animals. PI: Prof. Soad Ismail (2013)

Evaluation of some herbal Egyptian plants in treatment of some protozoal infections in experimental animals. PI:  Prof. Naimat Amer (2013)

Blastocystis hominis: Diagnosis, genomic analysis and in vitro treatment, with impact on the pathophysiological variability of different Blastocystis hominis isolates in experimental animals. PI: Prof. Soad Ismail (2014)

Novel diagnostic and therapeutic tools in marine models of hepato cellar   carcinoma a pilot study. PI: Prof. Eman El-Ahwany (2015)

Efficacy of the anti-parasitic agents mefloquine against schistosomiasis: in-vivo study. PI: Prof. Soad Ismail (2015)

Detection of infective stages of medically important parasites contaminating water bodies. PI: Prof. Sohair Sayed Mohammed (2016)

Effect of synthetic and natural agents on molecularly characterized cryptosporidium species: an experimental model. PI: Prof. Hoda Sabry (2016)

Potential role of Cryptosporidium in triggering intestinal neoplasia in a mouse model. PI: Prof. Maisa Ahmed Shalaby (2016)

Molecular and Immunohistochemical detection of Cryptosporidium-induced intestinal tissue alterations in dexamethasone treated &untreated mice. PI:  Prof. Naimat Amer (2016) 

 

  

    External Projects:    


  

 American University in Cairo: Nanoparticles as a delivery system for targeting Schistosomiasis and Fascioliasis: A pilot study using Nanotechnology and bioinformatics. PI: Prof. Suher Zada (2010)

El- Jameel center for Science and Technology & the American University in Cairo: Cloning expression of target antigen (Cathepsin L1&L2) from Schistosoma mansoni and Fasciola gigantica. PI: Prof. Suher Zada (2010)

Project STDF, ID 1454: Development of production and pegylation of interferon alpha. PI: Prof. Ehab El-Dabaa Mohammed Sabry (2010)

Egyptian and French Collaboration project (Lyon University): Development and evaluation of immunoblot and immunochromatography test kits for the diagnosis of helminthic infections in Egypt. PI: Prof. Ibrahim Rabie (2011)

Ministry of Scientific research: Nanotechnology based drug delivery for treatment of multi-drug resistant tuberculosis. PI: Prof. Mohammed Abbas Shemis (2011).

American University in Cairo: Treg cells, a new lymphocyte subpopulation with a key role in the immuno response against Schistosoma mansoni infection. PI: Prof. Suher Zada (2014)

A novel Nanotechnology based approach for the rapid diagnosis of infectious diseases using multiple nano- chip. PI: Prof. Ibrahim Rabie (2017)

  Publications


Publications in the Last Ten Years


 

  • Ibrahim Aly, Mona S. Gouida, Hoda E. L. Sayed, Sama M. N. Attiyah,Shaimaa Shaker, Noha A. Elleboudy and Samah . Ghoname(2020): Efficiency of Three Extracts of Carica papaya as Molluscicidal and Anti-schistosomal Agents against Biomphalaria alexandrina and Schistosoma mansoni by Flow Cytometry. Journal of Pharmaceutical Research International 32(11): 31-41.

  • Tarek K Zaalouk, Gamal A Abo-sheishaa and Ibrahim R Shalash (2020): Regulation of liver fibrosis during schistosoma mansoni infected mice .J. Egypt. Soc. Parasitol. (JESP), 50(2), 2020: 439 – 445.

  • TAREK K. ZAALOUK, GAMAL A. ABO SHEISHAA, AND IBRAHIM R. SHALASH(2020): Downregulation of toll-like receptor 4 and acute phase cytokines mediated dexamethasone immunosuppressant mechanism during cryptosporidium-parvum infection. J. Egypt. Soc. Parasitol. (JESP), 50(1): 197 – 202.

  • Rabab S. Zalata, Soad I. Hassan, Soheir S. Mahmoud , Mona Magdi, Hoda Sabry, Nevine Guirguis and Wafaa El-komy .(2020): Prominent effect of Mefloquine on Murine Schistosomiasis Mansoni Schistosomules with no detectable Hepatocyte P53 protein. Research Journal of Educational Research and Review (ISSN: 2315- 5132) Vol. 9(1) pp. 001-008, January, 2020.

  • Hanan El Baz, Zeinab Demerdash, Manal Kamel, Olfat Hammam, Dina Samir Abdelhady,Soheir Mahmoud, Salwa Hassan, Faten Mahmoud, Shimaa Atta,Nermine Magdi Riad, and Taghrid Gaafar (2020): Induction of Hepatic Regeneration in an Experimental Model Using Hepatocyte-Differentiated Mesenchymal Stem Cells. CELLULAR REPROGRAMMING ,Volume 22, Number 0, 2020, Mary Ann Liebert, Inc  .DOI: 10.1089/cell.2019.0076

  • EMAN E. A. METWALY, SAEDIA A. SAYEDEL-AHL, SOHEIR S. MAHMOUD and DOAA A. AHMED.(2020): EVALUATION OF PLUMBAGIN AS A POTENTIAL THERAPEUTIC AGENT FOR MURINE SCHISTOSOMIASIS MANSONI. Journal of the Egyptian Society of Parasitology, Vol.50, No.1, April 2020 J. Egypt. Soc. Parasitol. (JESP), 50(1), 2020: 1 – 9.

  • Hagar Abdel Maksoud, Hoda Sabry, Soheir Mahmoud, Nevine Guirguis , Rabab S. Zalat  Wafaa ELKomy , and Shaimaa El-Gohary.(2020): Evaluation of the therapeutic effect of some natural plant extracts on experimental cryptosporidiosis. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315-5132) Vol. 9(2) pp. 009-013, February 2020.

  • Eman El-Ahwany,Soheir S. Mansy,Mona Zoheiry,Lobna Mourad, Soheir Mahmoud,Hoda Abu-Taleb.(2020): MicroRNA-195 vector influence on the development of gradually induced hepatocellular carcinoma in murine model. Journal Ultrastructural pathology Volume 44, 2020- issue 2-https://doi.org/10.1080/01913123.2020.1744783

  • Alaa H Saleh, Abeer M Badr, Soheir S Mahmoud, Noha A Mahana and Ahmed S Abo Dena.(2020): In-vitro Investigation of the Effect of Bee Venom on Schistosoma mansoni Eggs. International Journal of Veterinary Science .P-ISSN: 2304-3075; E-ISSN: 2305-4360 Accepted: April 02, 2020 www.ijvets.com; editor@ijvets.com.

  • Additive Effect of Some Elements to vitamin B17 Administration in Immunosuppressed Mice Infected with Cryptosporidium.Soheir Mahmoud, Maisa Shalaby, Hoda Sabry, Neimat Amer,  Nevine Guirguis, Wafaa El Komy  Mennat  Al-Rahman, and Mona MagdyGlobal Advanced Research Journal of Educational Research and Reviews (GARJERR) ISSN: 2315-5132 November 2019, 8(1): pp. 001-005

  • Soheir S Mahmoud,Eman Aly,Zeinab H. Fahmy,Amal El Shenawy(2019): Effect of commiphora molmol(myrr) extract on mice infected by giardia lamblia.Journal of bioscience and medicine (7):50-66.

  •  Mahmoud SS,  Aly E,  FahmyZH., El Shenawy A (2019): Effect of Commiphora molmol (Myrrh) Extract on Mice Infected by Giardia lamblia. Journal of Biosciences and Medicines, 2019, 7, 50-60.

  • Lobna y.Ghanem1, Iman M. Mansour5, NellyAbulata5, Maha M.Akl3, ZeinabA. Demerdash2, HananG. El Baz2, Soheir S. Mahmoud, Salwa H. Mohamed2, Faten S. Mahmoud2 & Ayat S. M. Hassan1 ( 2019) : Liver Macrophage Depletion Ameliorates The Efect of Mesenchymal Stem Cell Transplantation in a Murine Model of Injured Liver  (Published: 10-1-2019 ) (2019) 9:35 | DOI:10.1038/s41598-018-37184-4

  • Marwa M.Abou El DahababSondos M.Shahata  Soheir S.M.Mahmoudc Noha A.Mahanaa (2019): In vitro effect of curcumin on Schistosoma species viability, tegument ultrastructure and egg hatchability   Author links open overlay panel Experimental Parasitology  .Available online 19 February 2019

In Press, Accepted ManuscriptWhat are Accepted Manuscript  articles?

  • Soheir S. Mahmoud, Eman Aly, Zeinab H. Fahmy, Amal El Shenawy. (2019): Effect of Commiphora molmol (Myrrh) Extract on Mice Infected by Giardia lamblia. Journal of Biosciences and Medicines, 2019, 7, 50-60 https://www.scirp.org/journal/jbm ISSN Online: 2327-509X  ISSN Print: 2327-5081

  • Sadek A , Alawam H , 3Fahmy A , Wafy W , Kasem M , Abd El Hady A, Hammam O , Mahmoud S , Sadek A A , Abd El Hady A A , Diab T.(2019):Effect of ozone/oxygen gas mixture on bilharzial hepatic fibrosis induced in infected mice.  International Journal of Medical Science and Innovative Research (IJMSIR) IJMSIR: A Medical Publication Hub Available Online at: www.ijmsir.com Volume – 4, Issue – 6, November - 2019, Page No. : 122 - 139

  • SoheirMahmoud, Maisa Shalaby ,Hoda Sabry, Neimat Amer, Nevine Guirguis, ,Wafaa El  Komy, Mennat Al-Rahman , and Mona Magdy.(2019): Additive Effect of Some Elements to vitamin B17 Administration in Immunosuppressed Mice Infected with Cryptosporidium. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315-5132) Vol. 8(1) pp. 1-5 October, 2019

  • Soad Ismail, Soheir Mahmoud, Hoda Sabri, Nevine Guirguis, Rabab Zalat and Wafaa El-komi.(2019): Comparative effect of Praziquantel and Mefloquine in Murine Schistosomal Resistance to Reinfection with Regards to Serum IL-4, IL-5 and IL-10 profiles. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315-5132) Vol. 8(1) pp. 6-16 October, 2019

  • Salwa F.Oshiba,Rania I.Ibraheem,Amal Mohamed Elshenawy,Hayam Abdel Samie, Aiad and Eman Ahmed ElWakil(2018): In vivo effect pomegraanat(punica granatum) extract versus Nitazoxanide drug on the ileum of experimentally infected mice with crypto parvum oocysts.Journal of American Science 14(2).

  • Histopathologic study and new natural therapeutic options of Blatocystis intestinal infectionMahmoud Tag, Faiza Osman, Soheir Atef, Maysa Shalaby, Ibraheim Rabee, Zeinab Fahmy, And Marwa Esmat.Egyptian journal of medical sciences Vol. 39(2) pp.601-619, December 2018.Immuno-histochemical changes triggered by repeated Cryptosporidium infection in immunosuppressed mice.

  • Mennat El-Rahman A. Fahmy; Hebat-Allah A. Yousof; Shaimaa H. El-Sayed; Soheir S. Mahmoud; Mona Magdy; Maisa A. Shalaby; Mousa A. M. Ismail :Journal of the Egyptian Society of ParasitologyArticle 1, Volume 48, Issue 3, Autumn 2018, Page 483-492 Detection rates of waterborne protozoa in water sources from Fayoum Governorate.

  • Maysa Mohamed Kamel Sobhy , Soheir Sayed Mahmoud , Shaimaa Helmy El-Sayed ,Enas Mohamed Ali Rizk , Amira Raafat , Mohamed Sherif Ismail Negm. (2018): Impact of treatment with a Protein Tyrosine Kinase Inhibitor (Genistein) on acute and chronic experimental Schistosoma mansoni Infection Experimental Parasitology 185 . 115e123.

  • Manal M. Kamel, Hanan G. El Baz, Zeinab Demerdash, Salwa Hassan. Faten Salah, Wafaa A. Mansour, Olfat Hammam, Shimaa Atta, Ali Bayoumi, Marwa Hassan, Soheir Mahmoud.(2018): Cord blood-derived mesenchymal stem cells with hepatogenic differentiation potential ameliorate chronic liver affection in experimental models. Adv Clin Exp Med. 2018;27(10):1329–1339.

  •  Ayman A. El-Badry , Sayeda M. Aufy , Eman S. El-Wakil,Enas M. Rizk , Soheir S. Mahmoud , Nahed Y. Taha (2018):First identification of Naegleria species and Vahlkampfia ciguana in Nile water, Cairo, Egypt: Seasonal morphology and phylogenetic analysis. Journal of Microbiology, Immunology and Infection (2018) xx, 1e7

  • Manal M. Kamel, Hanan G. El Baz, Zeinab Demerdash, Salwa Hassan. Faten Salah, Wafaa A. Mansour, Olfat Hammam, Shimaa Atta, Ali Bayoumi, Marwa Hassan, Soheir Mahmoud. (2018): Cord blood-derived mesenchymal stem cells with hepatogenic differentiation potential ameliorate chronic liver affection in experimental models. Adv Clin Exp Med. 2018; 27(10):1329–1339.

  •  MENNAT EL-RAHMAN A. FAHMY, HEBAT-ALLAH SALAH A. YOUSOF , SHAIMAA H. EL-SAYED , SOHEIR   S. MAHMOUD , MONA MAGDY , MAISA A. SHALABY AND MOUSA A. M. ISMAIL (2018): IMMUNO- HISTOCHEMICAL CHANGES TRIGGERED BY REPEATED CRYPTOSPORIDIUM INFECTION IN IMMUNOSUPPRESSED MICE . Journal Egypt . Soc. Parasitol. (JESP), 48(3), 483 – 492 483

  •  Mona M. Khatera , Shaimaa H. El-Sayedb , Hebat-Allah S. Yousofa , Soheir S. Mahmoud , Nadia El-Diba , Ayman A. El-Badrya (2018): Anti-Cryptosporidium efficacy of Olea europaea and Actinidia deliciosa in a neonatal mouse model. http://www.kamj.eg.net

  • Mona M. Khatera, Shaimaa H. El-Sayed, Hebat-Allah S. Yousofa,Soheir S. Mahmoud, Nadia El-Diba, Ayman A. El-Badrya (2017): Anti-Cryptosporidium efficacy of Olea europaea and Actinidia deliciosa in a neonatal mouse model. Kasr Al Ainy Medical Journal. http://www.kamj.eg.net.

  • Soheir S. Mansy, Eman El-Ahwany, Soheir Mahmoud, Sara Hassan, Mohammed I. Seleem, Amr Abdelaal, Ahmed H. Helmy, Mona K. Zoheiry, Ahmed S. AbdelFattah & Moataz H Hassanein .(2017) Potential ultrastructure predicting factors for hepatocellular carcinoma in HCV infected patients. ISSN: 0191-3123 (Print) 1521-0758 (Online) Journal homepage:

  • Pages 209-226 | Accepted 03 Apr 2017, Published online: 11 May 2017http://www.tandfonline.com/loi/iusp20,http://dx.doi.org/10.1080/01913123.2017.1316330

  • Soheir Mahmoud,Neimat Amer, Nevine Guirguisa, Ahmed H. HelmyM,Maisa Shalaby,WafaaElkomya and Hoda Sabry. (2017): POTENTIAL MODULATORY ROLE OF GLABRA AGAINST HEPATIC MORBIDITY IN CHRONIC MURINE SCHISTOSOMIASIS. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315-5132) Vol.6 (1) PP.005-011. Available online http://garj.org/garjerr/index.htm

  • Thabet Sakran; Gamal El-Shahawy; Maisa Shalaby; Hoda Sabry; Pessant Matooq; Almahy Elmallah Parasitologists united journal. Article 4, Volume 10, 1-2, December 2017, Page 30-38  Potential modulatory role of glycyrrhiza glabra against hepatic morbidity in chronic murine schistosomiasis Soheir Mahmoud,Neimat Amer, Nevine Guirguis, Ahmed H.Helmy ,Maisa Shalaby,wafaa elkomy and Hoda Sabry Global Advanced Research Journal of Educational Research and Review  Vol. 6(1) pp. 005-011, February, 2017

  • Shaimaa Helmy El-Sayed, Neimat Amer, Soad Ismail, Iman Ali, Enas Rizk, Mona Magdy and Ayman Abdel-Moamen El-Badry (2017): In Vitro and In Vivo Anti-blastocystis Efficacy of Olive Leaf Extract and Bee Pollen Compound. Research Journal of Parasitology, 12: 33-44.

  • Potential Effect of Camphor Oil as a Local Cercaricidal agent Nevine Guirguis Nessim, Sohair Mahmoud, Maisa Metwally, Hoda Sabri And Rabab Zalat. Global Advanced Research Journal of Educational Research and Review .Vol. 5(2) pp. 032- 037, February, (2016) Therapeutic effect of Lauric acid, a medium chain saturated fatty acid on Giardia lamblia in experimentally infected hamsters.

  • Soad Ismail , Iman Ali , Neimat Amer Zeinab Fahmy , Magda Azmy and Mona Magdy (2016) : Susceptibility of Blastocystis hominis to monolaurine (Lauric acid), lactoferine (Lactobacillus acidophillus) and metronidazole: An in vitro and in vivo studies. African Journal of Pharmacy and Pharmacology 10(2): 14-25

  • Omaima Mohammed ,Abou-Shady , Soheir Sayed Mohammed , Samar Sayed Attia , Hebat-Allah Salah Yusuf ,Dina Omar Helmy.(2016): Therapeutic effect of mefloquine on Schistosoma mansoni in experimental infection in mice. J Parasit Dis . 40(2):259–267

  • Nevine Griguis, Soheir Mahmoud, Rabab Zalat, Mona Magdy, and Eman Ali., (2016): Effect of Combined Albendazole and Sutrim in Experimental Toxoplasmosis. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315- 5132) Vol. 5(1) pp.009-012 http://www. garj.org/garjerr/index.html.

  • Nevine Guirguis Nessim, Soheir Mahmoud, Maisa Metwally, Hoda Sabri and Rabab Zalat. (2016): Potential Effect of Camphor Oil as a Local Cercaricidal Agent. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315- 5132) Vol. 5(2) pp. 032-037,

  • Available online http://garj.org/garjerr/index.htm

  • Wafaa El-komy, Soheir Mahmoud, Hoda Sabry, Soheir Mansy ; Nevine Gurguis.(2016). Changes in parasitic load, phagocytosis and ultra-structural pattern in experimental cryptosporidiosis following combined (Antox and Nitazode) treatment. Global Advanced Research Journal of Educational Research and Review (ISSN: 2315- 5132) Vol. 5(3) pp, 038-044

       Available online http://garj.org/garjerr/index.htm

  •  Amal Ammar ,Nabil El Hefawy , Soheir Mahmoud ;Hoda Sabry ,Fathyia  Gawish ,Ibrahim Aly  and Laila  Refahy (2016). : Evaluation of  Callistemon Citrinus ,Punicagranatum and Pumpkinainst molluscicidal and free larval stages of Schistosoma mansoni. International Journal of Biology, Pharmacy and Allied Sciences (IJBPAS) , 5(11): 2863-2884

  • Ahmed M.S. Bayoumy, Basma, M. Abou El-Nour and Eman Ali (2015): A Comparative Parasitological Study on Treatment of Hymenolepis nana among Immunocompetent and Immunocompromised Infected Mice. Global Veterinaria 15 (4): 414-422.

  • Eman Ali Mohamed, Rabab S. Zalat, Mona Magdi, Nevine Guirguis and Soheir Mahmoud (2015): Effect of Combined Therapy with Albendazole and Sutrim in Experimental Cryptosporidiosis. Global Veterinaria 15 (2): 144-149.

  • Ibrahim Aly, Rabab Zalat, Gehan El-Enain, Eman Aly (2015) : Comparison between Modified Acid Fast Staining and Antigen Detection Assay as Diagnostic Techniques for Cryptosporidium parvum .World Journal of Medical Sciences 13 (1): 72-78.

  •  Mohamed Abdel-Wahab El-Emam1, Soheir Sayed Mahmoud, Fatma EL-Zahraa Anwar Bayaumy(2015). Potential role of mefloquine (antimalarial drug) and methanol extract of Chenopodium ambrosioides and Sesbania sesban in mice infected with Schistosoma mansoni. Asian Pac J Trop Dis 2015; 5(8):930-935.

  •  Mohamed Abdel-Wahab El-Emam1, Soheir Sayed Mahmoud, Fatma EL-Zahraa Anwar Bayaumy(2015). Potential role of mefloquine (antimalarial drug) and methanol extract of Chenopodium ambrosioides and Sesbania sesban in mice infected with Schistosoma mansoni. Asian Pac J Trop Dis 2015; 5(8):930-935. www.elsevier.com/locate/apjtd

  • Eman Ali Mohamed;Rabab S. Zalat; Mona Magdi; Nevine Guirguis and Soheir Mahmoud. (2015): Effect of combined therapy with Albendazole and Sutrim in experimental cryptosporidiosis. Global Veterinaria 15 (2): 144-149.

  • Omaima Mohammed Abou–shady; Soheir Sayed Hohammed; Sammar Sayed Attia;Hebat –Allah Salah Yusuf  and Dina Omar Helmy.(2015 ) In vitro effect of mefloquine on Adult Schistosoma mansoni. Research Journal of Parasitology 10(3):111-119.

  • Zeinab Hassanein Fahmy , Eman Aly and Olfat Hammam (2015): The role of artemether as a possible drug for treatment Blastocystis hominis infection: In vivo and in vitro studies. African Journal of Pharmacy and Pharmacology 9(36): 893-899.

  • Mohamed Abass, Heba Hassan, Eman Ali Mohamed, Rabab S. Zalat, Mona Magdi and Amal A. El-Shenawy (2015): Efficacy of Newly Introduced Synthetic Compounds for Treatment of Experimental Intestinal Giardiasis. Global Veterinaria 15 (2): 215-222.

  •  Eman Al-Sayed, Hoda Abdel Hamid , Hanaa M. Abu El Einin, Eman Ali, Zeinab Fahmy (2014):  Antiprotozoal and molluscicidal activities of Pelargonium graveolens. Int J Pharm 4(4):209-214.

  • Eman M Aly, Hoda Y Sabry, Zeinab H Fahmy, Rabab S Zalat (2014) : Efficacy of combination therapy (metronidazole and/or artemether) in experimental giardiasis and its impact on nonenzymatic oxidative stress biomarkers. Parasitologistis united journal 7(1):68-74.

  • Amal, I.A. Ammar; Soheir, S.M. Mahmoud and N.N. El Hefnawy (2014): Effect of Ginger on hamsters infected by Giardia lamblia. Journa of Environmental studies and researches .1(1): 45-56.

  • Ayman A. El-Badry, Yaser A. El-Badry,Soheir  S. Mahmoud ,Shaimaa H. El-Sayed, Maha. M.A. Basyoni. (2014): Anti-Schistosomal activity of Mefloquine-Silver nano-particles composite in Schistosoma mansoni-infected mice. EPU IV Conference. Accepted for Publication in the Parasitologists United Journal

  • Hebat-Allah S. Yousof, Soheir S. Mahmoud, Samar S. Attia, Dina O.Helmy, Omaima M.Abou-Shady.(2014): In Vitro Evaluation of the Direct Effect of Mefloquine on Adult S. mansoni Worms. EPU IV Conference. Accepted for Publication in the Parasitologists United Journal

  • Mona M. Khater, Shaimaa H. El-Sayed, Hebat-Allah S. Yousof, Soheir S. Mahmoud, Ayman A. El-Badry. (2014): Anti-Cryptosporidium Activity of Olea europaea and Actinidia deliciosa in Experimentally Infected Mice .EPU IV Conference. Accepted for Publication in the Parasitologists United Journal

  • 16-Maysa M.K. Sobhy, Soaad I. Hassan, Ayman A. El-Badry, Shaimaa H. El-Sayed , Soheir S. Mahmoud, Olfat A. Hammam, Hoda Y.Sabry. (2014): Tissue mast cells density in mefloquine, artemether and praziquantel treated Schistosoma mansoni infected mice. 6th ASEAN Congress of Tropical Medicine and Parasitology GLOBAL CHALLENGES IN TROPICAL DISEASES: Bridging Gaps and Building Partnerships 5-7 March Intercontinental Kuala Lumpur, Malaysia P .106.

  • 17Ali Eman ; Zalat, Rabab; Magdi Heba2, Guirguis Nevine , and Mahmoud Soheir. (2014): Effect of combined therapy with Albendazole and Sutrim in experimental cryptosporidiosis. 13thInternational Congress of parasitology August 10th - 15 th 2014. At the Camino Real Hotel  Mexico City.                      

  • Zeinab Hassanein Fahmy, Eman Aly , Ibrahim shalsh and Amira H. Mohamed (2014) : The effect of medium chain saturated fatty acid (monolaurin) on levels of the cytokines on experimental animal in Entamoeba histolytica and Giardia lamblia infection . African Journal of Pharmacy and Pharmacology 8(4): 106-114.

  • D. Kamel, A. Farid, E. Ali, I. Rabia, M. Hendawy and A.M. El Amir (2013): Diagnostic Potential of Target Giardia lamblia Specific Antigen for Detection of Human Giardiasis Using Coproantigen Sandwich ELISA. World Journal of Medical Sciences 9 (2): 113-122.

  • Mona M.Aly, Maisa A.Shalaby, Samar S.Attia, Shaimaa H.ElSaid and Soheir S.Mahmoud. Parasitologists united journal.Vol. 6 (1) pp. 89-98, 2013

  • Yasmeen M Attia1, Essam F Elalkamy, Olfat A Hammam, Soheir S Mahmoud and Aiman S El-Khatib. (2013):Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection. Parasites &Vectors. 6:199-211.   http://www.parasitesandvectors.com/content/6/1/199.

  • Shaimaa H. El-Sayed1, Maysa M.K. Sobhhy, Soaad I. Hassan, Nagwa T. Elkhafef, Soheir S. Mahmoud, Olfat A. Hamam, Ayman A. El-Badry (2013): Role of Mefloquine in Murine Schistrosomiasis mansoni as A Prophylactic and Chemotherapeutic Agent. Accepted for Publication in the Parasitologists United Journal

  •  Mona M. Aly, Maisa A. Shalaby, Samar S. Attia, Shaimaa H. El Said, Soheir S. Mahmoud: (2013) Therapeutic Effect of Lauric Acid, A Medium Chain Saturated Fatty Acid on Giardia lamblia in Experimentally Infected Hamsters. Parasitologists United Journal  6 (1): 89-98

  • Demerdash Z., Baz H. El , Mahmoud F. , Mohamed S. , Maher K., Gaafar T. , Shawky S. , Hassan M., Abdelhady D.  and Taha T.(2013): Enhancing ex vivo expansion of cord blood-derived unrestricted somatic stem cells for clinical applications .Cell Prolif.,  46, 628–636

  • Fahmy ZH, El Komy W, Ali EM, Hoda Sabry (2012): Immunolocalization of Cercarial Secretory Antigen on Different Life stages of S.mansoni Infected Mice using Immunoperoxidase . Parasitologistis united journal 5(1):35-40.

  • El-Sayed S.H., Kamel M.M., Hassan S.I., El-Badry A.A., Mahmoud S.S., Hamam O.A. (2012): Resistance to re-infection with Schistosoma mansoni in mice treated with Mefloquine .XI EUROPEAN MULTICOLLOQUIUM OF PARASITOLOGY EMOP XI  CLUJ- Napoca , Eomania :25-29 July 2012.http://www.zooparaz.net/emop11

  •  Rashika El Ridia, Hatem Tallimaa, Mohamed Salahb, Marwa Aboueldahabc, Omar M. Fahmya, Mohammad Farhan Al-Halbosiya, Soheir S. Mahmoud.( 2012 ). Efficacy and mechanism of action of arachidonic acid in the treatment of hamsters infected with Schistosoma mansoni or Schistosoma haematobium. International Journal of Antimicrobial Agents .Mar;39(3):232-9.   http://www.elsevier.com/locate/ijantimicag

  • Fouad Yousif, Gamila Wassel, Loutfy Boulos, Therese Labib, Khaled Mahmoud Salwa El-Hallouty, Samia El Bardicy, Soheir Mahmoud, Fatem Ramzy, Lamiaa Gohar, May El-Manawaty, Mohamed A. M. El Gendy, Walid Fayad, and Bassem El-Menshawi (2012): Contribution to in vitro screening of Egyptian plants for schistosomicidal activity. Pharmaceutical Biology, 50(6): 732–739.http://informahealthcare.com/doi/abs/10.3109/13880209.2011.625952

  • Wafaa El Komy, Rabab S Zalat, Eman Ali,  Mona M Nosseir (2011): Antiprotozool Activity  of  Nitazoxanide in Hamsters Experimentally Infected with Giardia Lamblia or Entameba histolytica. The New Egyptian Journal of Medicine 45(5):448-456.

  • Kamel E.G., M.A. El-Emam , S.S.M. Mahmoud , F.M. Fouda, F.E. Bayaumy.( 2011): Parasitological and biochemical parameters in Schistosoma mansoni-infected mice treated with methanol extract from the plants Chenopodium ambrosioides, Conyza dioscorides and Sesbania sesban. Parasitology International 60 (2011) 388–392.http://trove.nla.gov.au/work/159472486?q&versionId=173829181

  • Reem O.A.Kamel, Ibrahim R.Aly, Soheir S Mahmoud and Neven A. Madboly. (2011): Evaluation of the anthelmintic effects of Artemether against experimental S.mansoni infection in mice using different time periods of treatment. J.Egypt.Ger.Soc.Zool. vol.( 63d): Invertebrate Zoology &Parasitology, 181-198. Http//:www.egsz.com

  • Ibrahim Rabia , Faten Nagy, Eman Aly , Amina Mohamed, Fayza EL-Assal and Azaa ElAmir (2010): Effect of Treatment with Antifibrotic Drugs in Combination with PZQ in Immunized Schistosoma mansoni Infected Murine Model. The journal of American Science 2010 6(5):208-216.

  • Rabia I, Hendawy M.A., Ali E.M, Mohamed S.Hedaya, M.S and Nosseir M.F (2010): The effect of Diphenyl Dimethyl Bicarboxylate and Dexamethasone on Immunological and parasitological parameters in murine Schistosomiasis mansoni. Mem Inst Oswaldo Cruz,Rio de Janerio105(6):000-000.

  • Tarek M. Diab, Heba H. Mansour Soheir S. Mahmoud, (2010): Fasciola gigantica: Parasitological and Scanning Electron Microscopy Study of the in vitro Effects of Ivermectin and/or Artemether. Experimental parasitology124, 279-284.PMID: 19861124 [PubMed - indexed for MEDLINE

  • Ramzy F, Mahmoud S, William S. (2010):Further assessment of Mirazid as antischistosomal drug in experimental schistosomiasis hematobium. Publication in Pharmaceutical Biology. 48(7):775-9. http://www.ncbi.nlm.nih.gov/pubmed

  •  Draz HM, Mahmoud SS, Ashour E, Shaker YM, Wu CH, Wu Y. (2010):Effects of PEG-interferon-alpha-2A on schistosoma mansoni infection in mice. J .parasitol. 96(4):703-708.

  • PMID: 20486736 [PubMed - indexed for MEDLINE

  • E.G. Kamel , M.A. El-Emam , S.S.M. Mahmoud , F.M. Fouda , F.E. Bayaumy ,(2010):Attenuation of Schistosoma mansoni cercarial infectivity to albino mice by methanol extract of some plant species, Pesticide Biochemistry and Physiology 98 (2010) 342–348.

  • http://www.researchgate.net/publication/232380798

  • Lobna Y Ghanem, Uta Dahmen, Olaf Dirsch, Mona MF Nosseir, Soheir S Mahmoud, Wafaa AF Mansour .(2010) : Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis?, World J Hepatol . 2(12): 434-441.    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010513/